Fluridil (Topilutamide, Eucapil) is an Androgen Inhibitor medication. Fluridil is available as a topical medication that is primarily used as a treatment for androgenic alopecia (hormone-induced hair loss). Fluridil is rarely used as a treatment for acne. Fluridil is not available in all countries.

Androgen hormones stimulate the growth and activity of the sebaceous glands and production of sebum, both of which contribute to acne symptoms in some individuals. The elevated levels of androgen hormones during puberty can cause acne in some individuals. Studies of adult females with acne have shown that many of these women have abnormally high levels of androgen hormones in their blood. Fluridil may help improve acne symptoms by reducing the effect of elevated androgen levels.