Medroxyprogesterone is a Hormonal Contraceptive (birth control) medication. Medroxyprogesterone is a synthetic analogue of the female hormone Progesterone. Medrocyprogesterone is used as a long-lasting injectable contraceptive (eg. Depo-Provera).
Hormonal contraceptives are not frequently used as a primary treatment for acne, but many women report substantial changes in their acne symptoms after starting use of Hormonal Contraceptives.
Hormones have a major impact on acne symptoms. Female sex hormones (eg. Estrogen, Progesterone) and male sex hormones (eg. Testosterone) control many important functions within the body. Use of Hormonal Contraceptives has been shown to improve acne in some women and worsen it in others, with comparable frequency. Hormonal Contraceptives may improve acne symptoms in some women by blocking the effect of androgen (male) hormones. Androgen hormones can increase the activity of the sebaceous glands and sebum production, which can contribute to the development of acne.
Depo-M, Depo-Provera, Meprate