Azithromycin is an antibiotic in the Macrolide Family. Azithromycin is a very common antibiotic that is used to treat many different kinds of infections.

Azithromycin is rarely used to treat acne. However, there are some reports that Azithromycin helped improve acne symptoms. Antibiotic susceptibility testing indicates that the acne-causing P. acnes bacterium tends to be susceptible to antibiotics in the Macrolide family, including Azithromycin. However, Macrolide-resistant P. acnes bacteria are becoming common in many regions of the world.