Clindamycinis an antibiotic in the Lincosamide Family. Clindamycin is closely related to antibiotics in the Macrolide family (eg. Erythromycin, Azithromycin). It is used to treat a variety of bacterial infections.

Clindamycin is frequently used as a treatment for acne. Topical Clindamycin is one of the most common antibiotic treatments for acne. Oral Clindamycin is also occasionally used as to treat acne. Many patients have reported that Clindamycin helped to improve their acne symptoms. Their is also a wealth of clinical research that demonstrates that Clindamycin can be an effective acne treatment.

Laboratory antibiotic susceptibility testing indicates that the acne-causing P. acnes bacterium is usually sensitive to Clindamycin. However, Clindamycin-resistant P. acnes bacteria are becoming common in many regions of the world. Individuals with acne symptoms that are caused by Clindamycin-resistant bacteria are not likely to benefit from this medication. Bacteria that are resistant to Clindamycin are often also resistant to Macrolide antibiotics, such as Erythromycin.

Topical Clindamycin is often combined with complementary treatments, such as oral antibiotics, retinoids or light-based treatments.