Demeclocycline (Declomycin) is an antibiotic in the Tetracycline family. Demeclocycline is a wide spectrum antibiotic that is used to treat a range of bacterial infections, including acne.

Demeclocycline is rarely used to treat acne, but other Tetracycline family antibiotics (eg. Minocycline, Doxycycline, Tetracycline) are commonly used as acne treatments.

Tetracycline family antibiotics can be very effective treatments for moderate to severe acne, but tetracycline-resistant acne infections are becoming increasingly common in many places.