Sulfafurazole is an antibiotic in the Sulfonamide family. It is a short-lived antibiotic that is active against certain types of gram-positive and gram-negative bacteria. This medication is not available in all countries and it is not a commonly used medication.
Sulfisoxazole is rarely used to treat acne. For the treatment of active acne symptoms, other Sulfonamide family antibiotic (eg. Sulfamethoxazole, Dapsone, Silver Sulfadiazine) are much more commonly used.